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pentobarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of CYP3A4 inducers might lower sufentanil stages and efficacy, maybe precipitating withdrawal syndrome in patients who've created physical dependence to sufentanil. Discontinuation of concomitant

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